BDBM202628 US9242943, 37

SMILES COc1cnc2c(Nc3cccc(c3)C3(C)COCC(N)=N3)cccc2c1

InChI Key InChIKey=IGUZINVHWNCBIH-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 202628   

TargetBeta-secretase 2(Human)
Siena Biotech

US Patent
LigandPNGBDBM202628(US9242943, 37)
Affinity DataIC50: 120nMAssay Description:The assay uses the principle of inhibition of human TMEM27 cleavage by endogenous cellular BACE2 in the Ins1e rat cell line and shedding from the cel...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/28/2016
Entry Details
US Patent