BDBM203850 (2E)-2-[(2-chloro-3,4-dimethoxyphenyl)methylidene]-5,8-dimethoxy-1,2,3,4-tetrahydronaphthalen-1-one (3w)

SMILES COc1ccc(OC)c2C(=O)\C(CCc12)=C\c1ccc(OC)c(OC)c1Cl

InChI Key InChIKey=CKIDQUFHKZLIJZ-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 203850   

TargetAcetylcholinesterase(Electric eel)
Wuhan University of Technology

LigandPNGBDBM203850((2E)-2-[(2-chloro-3,4-dimethoxyphenyl)methylidene]...)
Affinity DataIC50: 2.40E+3nMpH: 8.0 T: 2°CAssay Description:This spectrophotometric assay is based on the reaction of 5,5-dithio-bis(2-nitrobenzoic)acid (DTNB) with thiocholine to yield a colored product. Shim...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/29/2016
Entry Details Article
PubMed
TargetCarboxylic ester hydrolase(Horse)
Wuhan University of Technology

LigandPNGBDBM203850((2E)-2-[(2-chloro-3,4-dimethoxyphenyl)methylidene]...)
Affinity DataIC50: 2.47E+4nMpH: 8.0 T: 2°CAssay Description:This spectrophotometric assay is based on the reaction of 5,5-dithio-bis(2-nitrobenzoic)acid (DTNB) with thiocholine to yield a colored product. Shim...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/29/2016
Entry Details Article
PubMed
TargetAmine oxidase [flavin-containing] A(Rat)
Wuhan University of Technology

LigandPNGBDBM203850((2E)-2-[(2-chloro-3,4-dimethoxyphenyl)methylidene]...)
Affinity DataIC50: 1.00E+5nMpH: 7.4 T: 2°CAssay Description:A fluorimetric method reported by Matsumoto et al.[T. Matsumoto, O. Suzuki, T. Furuta, M. Asai, Y. Kurokawa, Y. Nimura, Y. Katsumata, I. Takahashi. C...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/29/2016
Entry Details Article
PubMed
TargetAmine oxidase [flavin-containing] B(Rat)
Wuhan University of Technology

LigandPNGBDBM203850((2E)-2-[(2-chloro-3,4-dimethoxyphenyl)methylidene]...)
Affinity DataIC50: 1.00E+5nMpH: 7.4 T: 2°CAssay Description:A fluorimetric method reported by Matsumoto et al.[T. Matsumoto, O. Suzuki, T. Furuta, M. Asai, Y. Kurokawa, Y. Nimura, Y. Katsumata, I. Takahashi. C...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/29/2016
Entry Details Article
PubMed