BDBM203859 2-(2-Chloro-3,4-dimethoxy-benzylidene)-7-nitro-tetralone (3af)

SMILES COc1ccc(\C=C2/CCc3ccc(cc3C2=O)[N+]([O-])=O)c(Cl)c1OC

InChI Key InChIKey=IMBQPNJFSWFYGV-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 203859   

TargetAcetylcholinesterase(Electric eel)
Wuhan University of Technology

LigandPNGBDBM203859(2-(2-Chloro-3,4-dimethoxy-benzylidene)-7-nitro-tet...)
Affinity DataIC50: 2.92E+3nMpH: 8.0 T: 2°CAssay Description:This spectrophotometric assay is based on the reaction of 5,5-dithio-bis(2-nitrobenzoic)acid (DTNB) with thiocholine to yield a colored product. Shim...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/29/2016
Entry Details Article
PubMed
TargetCarboxylic ester hydrolase(Horse)
Wuhan University of Technology

LigandPNGBDBM203859(2-(2-Chloro-3,4-dimethoxy-benzylidene)-7-nitro-tet...)
Affinity DataIC50: 1.75E+4nMpH: 8.0 T: 2°CAssay Description:This spectrophotometric assay is based on the reaction of 5,5-dithio-bis(2-nitrobenzoic)acid (DTNB) with thiocholine to yield a colored product. Shim...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/29/2016
Entry Details Article
PubMed
TargetAmine oxidase [flavin-containing] A(Rat)
Wuhan University of Technology

LigandPNGBDBM203859(2-(2-Chloro-3,4-dimethoxy-benzylidene)-7-nitro-tet...)
Affinity DataIC50: 1.24E+3nMpH: 7.4 T: 2°CAssay Description:A fluorimetric method reported by Matsumoto et al.[T. Matsumoto, O. Suzuki, T. Furuta, M. Asai, Y. Kurokawa, Y. Nimura, Y. Katsumata, I. Takahashi. C...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/29/2016
Entry Details Article
PubMed
TargetAmine oxidase [flavin-containing] B(Rat)
Wuhan University of Technology

LigandPNGBDBM203859(2-(2-Chloro-3,4-dimethoxy-benzylidene)-7-nitro-tet...)
Affinity DataIC50: 2.90E+3nMpH: 7.4 T: 2°CAssay Description:A fluorimetric method reported by Matsumoto et al.[T. Matsumoto, O. Suzuki, T. Furuta, M. Asai, Y. Kurokawa, Y. Nimura, Y. Katsumata, I. Takahashi. C...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/29/2016
Entry Details Article
PubMed