BDBM20534 4-Oxopyrimidine, 27b::6-({6-[4-(trifluoromethyl)phenyl]pyrimidin-4-yl}oxy)isoquinoline

SMILES FC(F)(F)c1ccc(cc1)-c1cc(Oc2ccc3cnccc3c2)ncn1

InChI Key InChIKey=ITOOUJYTHCCASB-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 20534   

LigandPNGBDBM20534(6-({6-[4-(trifluoromethyl)phenyl]pyrimidin-4-yl}ox...)
Affinity DataIC50: 1.40E+3nMpH: 7.4 T: 2°CAssay Description:TRPV1 activities were monitored as a function of cellular uptake of radioactive calcium (45Ca2+). The test compounds were preincubated with TRPV1 exp...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/28/2008
Entry Details Article
PubMed
LigandPNGBDBM20534(6-({6-[4-(trifluoromethyl)phenyl]pyrimidin-4-yl}ox...)
Affinity DataIC50: 4.00E+3nMAssay Description:TRPV1 activities were monitored as a function of cellular uptake of radioactive calcium (45Ca2+). The test compounds were preincubated with TRPV1 exp...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/28/2008
Entry Details Article
PubMed