BDBM20546 4-Oxopyrimidine, 29a::8-({6-[4-(trifluoromethyl)phenyl]pyrimidin-4-yl}oxy)quinolin-2-ol

SMILES FC(F)(F)c1ccc(cc1)-c1cc(Oc2cccc3ccc(=O)[nH]c23)ncn1

InChI Key InChIKey=KZUFJUZSABLGKS-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 20546   

LigandPNGBDBM20546(8-({6-[4-(trifluoromethyl)phenyl]pyrimidin-4-yl}ox...)
Affinity DataIC50: 4.00E+3nMpH: 7.4 T: 2°CAssay Description:TRPV1 activities were monitored as a function of cellular uptake of radioactive calcium (45Ca2+). The test compounds were preincubated with TRPV1 exp...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/28/2008
Entry Details Article
PubMed
LigandPNGBDBM20546(8-({6-[4-(trifluoromethyl)phenyl]pyrimidin-4-yl}ox...)
Affinity DataIC50: 4.00E+3nMAssay Description:TRPV1 activities were monitored as a function of cellular uptake of radioactive calcium (45Ca2+). The test compounds were preincubated with TRPV1 exp...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/28/2008
Entry Details Article
PubMed