BDBM20563 N-[4-({6-[4-(trifluoromethyl)piperidin-1-yl]pyrimidin-4-yl}oxy)-1,3-benzothiazol-2-yl]acetamide::Piperazinylpyrimidine analogue, 14

SMILES CC(=O)Nc1nc2c(Oc3cc(ncn3)N3CCC(CC3)C(F)(F)F)cccc2s1

InChI Key InChIKey=DIEWRDPAJIXNPT-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 20563   

LigandPNGBDBM20563(N-[4-({6-[4-(trifluoromethyl)piperidin-1-yl]pyrimi...)
Affinity DataIC50: 19nMAssay Description:TRPV1 activities were monitored as a function of cellular uptake of radioactive calcium (45Ca2+). The test compounds were preincubated with TRPV1 exp...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/28/2008
Entry Details Article
PubMed
LigandPNGBDBM20563(N-[4-({6-[4-(trifluoromethyl)piperidin-1-yl]pyrimi...)
Affinity DataIC50: 330nMAssay Description:Antagonist activity at rat TRPV1More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2024
Entry Details
PubMed
LigandPNGBDBM20563(N-[4-({6-[4-(trifluoromethyl)piperidin-1-yl]pyrimi...)
Affinity DataIC50: 330nMpH: 7.4 T: 2°CAssay Description:TRPV1 activities were monitored as a function of cellular uptake of radioactive calcium (45Ca2+). The test compounds were preincubated with TRPV1 exp...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/28/2008
Entry Details Article
PubMed