BDBM206058 5-(4-((1-(4-((1R,3R)-2-(2,2-difluoroethyl)- 3-methyl-2,3,4,9-tetrahydro-1H- pyrido[3,4-b]indol-1-yl)-3- methoxyphenyl)piperidin-4- yl)methyl)piperazin-1-yl)-N-((R)-2,6- dioxopiperidin-3-yl)picolinamide formate::US20260007681, Compound A57

SMILES COc1cc(N2CCC(CN3CCN(c4ccc(C(=O)N[C@@H]5CCC(=O)NC5=O)nc4)CC3)CC2)ccc1[C@@H]1c2[nH]c3ccccc3c2C[C@@H](C)N1CC(F)F

InChI Key InChIKey=OYMOSSFRFJBEGC-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 206058   

TargetDNA damage-binding protein 1/Protein cereblon(Human)
University Of Michigan

US Patent
LigandChemical structure of BindingDB Monomer ID 206058BDBM206058(5-(4-((1-(4-((1R,3R)-2-(2,2-difluoroethyl)- 3-meth...)
Affinity DataIC50: 50nMAssay Description:Source (MLPCN Center Name): The Scripps Research Institute Molecular Screening Center (SRIMSC) Center Affiliation: The Scripps Research Institute (TS...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/20/2026
Entry Details
US Patent