BDBM20675 ethyl N-[3-({6-[(2S)-butan-2-ylcarbamoyl]-5-methylpyrrolo[1,2-a][1,2,4]triazin-4-yl}amino)-4-methylphenyl]carbamate::pyrrolo[2,1-f][1,2,4]triazine analogue, 21i

SMILES CCOC(=O)Nc1ccc(C)c(Nc2ncnn3cc(C(=O)N[C@@H](C)CC)c(C)c23)c1

InChI Key InChIKey=WXIRVUHFCVUGCN-UHFFFAOYSA-N

Data  1 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 20675   

TargetMitogen-activated protein kinase 14(Human)
Novartis Pharmaceuticals

LigandPNGBDBM20675(ethyl N-[3-({6-[(2S)-butan-2-ylcarbamoyl]-5-methyl...)
Affinity DataIC50: 5.60nM EC50:  47nMAssay Description:The kinase activity was determined by quantitation of the amount of radioactive phosphate transferred to myelin basic protein (MBP) with or without i...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/16/2008
Entry Details Article
PubMed