BDBM206759 US9260446, (I-R)::US9695185, I-R

SMILES FC(F)(F)c1ccc(CN2C(=O)[C@]3(COc4cc5OCOc5cc34)c3ccccc23)o1

InChI Key InChIKey=NEBUOXBYNAHKFV-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 206759   

TargetSodium channel protein type 9 subunit alpha(Human)
Xenon Pharmaceuticals

US Patent
LigandPNGBDBM206759(US9695185, I-R | US9260446, (I-R))
Affinity DataIC50: 4.20E+3nMAssay Description:The assay is based on the guanidine influx assay described by Reddy, N. L., et al., J. Med. Chem. (1998), 41(17):3298-302. The guanidine influx assay...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/28/2016
Entry Details
US Patent

TargetSodium channel protein type 9 subunit alpha(Human)
Xenon Pharmaceuticals

US Patent
LigandPNGBDBM206759(US9695185, I-R | US9260446, (I-R))
Affinity DataIC50: 4.20E+3nMAssay Description:A radiotracer flux assay used to determine ion flux activity of voltage-gated sodium channels in a high-throughput microplate-based format. The assay...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/26/2018
Entry Details
US Patent