BDBM20796 2-amino-6-halopurine analogue, 19d::2-amino-9-[(2-bromo-3,4,5-trimethoxyphenyl)methyl]-9H-purine-6-thiol

SMILES COc1cc(Cn2cnc3c2nc(N)[nH]c3=S)c(Br)c(OC)c1OC

InChI Key InChIKey=RWNQSAJAMOFEFO-UHFFFAOYSA-N

Data  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 20796   

TargetHeat shock protein HSP 90-beta(Human)
Biogen Idec

LigandPNGBDBM20796(2-amino-9-[(2-bromo-3,4,5-trimethoxyphenyl)methyl]...)
Affinity DataEC50:  1.00E+5nMpH: 7.2 T: 2°CAssay Description:EC50 was defined as the concentration of the compound at which there was 50% degradation of the Her-2/neu protein in MCF7 breast carcinoma cells. Sam...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/17/2008
Entry Details Article
PubMed