BDBM20804 2-[(2-amino-6-chloro-9H-purin-9-yl)methyl]-4-methoxy-3,5-dimethyl-1-oxidopyridin-1-ium::2-amino-6-halopurine analogue, 24::6-Chloro-9-(4-methoxy-3,5-dimethyl-N-oxypyridin-2-ylmethyl)-9H-purin-2-ylamine

SMILES COc1c(C)c[n+]([O-])c(Cn2cnc3c(Cl)nc(N)nc23)c1C

InChI Key InChIKey=FLKOQKIGYYKSHM-UHFFFAOYSA-N

Data  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 20804   

TargetHeat shock protein HSP 90-beta(Human)
Biogen Idec

LigandPNGBDBM20804(2-[(2-amino-6-chloro-9H-purin-9-yl)methyl]-4-metho...)
Affinity DataEC50:  80nMpH: 7.2 T: 2°CAssay Description:EC50 was defined as the concentration of the compound at which there was 50% degradation of the Her-2/neu protein in MCF7 breast carcinoma cells. Sam...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/17/2008
Entry Details Article
PubMed