BDBM20814 2-amino-6-halopurine analogue, 36::6-chloro-9-[(4-methanesulfinyl-3,5-dimethylpyridin-2-yl)methyl]-9H-purin-2-amine

SMILES Cc1cnc(Cn2cnc3c(Cl)nc(N)nc23)c(C)c1S(C)=O

InChI Key InChIKey=RYSJCXRKXGOBKQ-UHFFFAOYSA-N

Data  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 20814   

TargetHeat shock protein HSP 90-beta(Human)
Biogen Idec

LigandPNGBDBM20814(6-chloro-9-[(4-methanesulfinyl-3,5-dimethylpyridin...)
Affinity DataEC50: >1.00E+4nMAssay Description:EC50 was defined as the concentration of the compound at which there was 50% degradation of the Her-2/neu protein in MCF7 breast carcinoma cells. Sam...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/17/2008
Entry Details Article
PubMed