BDBM208947 US9266880, 4

SMILES Cn1cncc1-c1ccnc2n(ncc12)-c1ccc(F)cc1

InChI Key InChIKey=JFEMPGINTWTZJM-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 208947   

TargetSteroid 17-alpha-hydroxylase/17,20 lyase(Human)
Bristol-Myers Squibb

US Patent
LigandPNGBDBM208947(US9266880, 4)
Affinity DataIC50: 50nMpH: 7.2 T: 2°CAssay Description:The assays were performed in U-bottom 384-well optiplates. The final assay volume was 15 ul prepared from 7.5 ul additions of microsomes (prepared as...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/17/2017
Entry Details
Go to US Patent

TargetSteroid 17-alpha-hydroxylase/17,20 lyase(Human)
Bristol-Myers Squibb

US Patent
LigandPNGBDBM208947(US9266880, 4)
Affinity DataIC50: 50nMAssay Description:Inhibition of human CYP17A1More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/18/2024
Entry Details
PubMed
TargetCytochrome P450 1A2(Human)
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM208947(US9266880, 4)
Affinity DataIC50: 58nMAssay Description:Inhibition of CYP1A2 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/18/2024
Entry Details
PubMed