BDBM209568 US9271969, 56

SMILES OC(=O)C[C@H]1CCC(CC1)c1ccc(cc1)-c1cn2cc(nc2s1)C(=O)NCc1ccc(OC(F)(F)F)cc1

InChI Key InChIKey=IALTYDHGZCHKJE-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 209568   

TargetDiacylglycerol O-acyltransferase 1(Human)
Kainos Medicine

US Patent
LigandPNGBDBM209568(US9271969, 56)
Affinity DataIC50: 10nMpH: 7.4 T: 2°CAssay Description: Assay buffer [20 mM HEPES (pH 7.4), 100 mM MgCl2 and 0.04% bovine serum albumin (BSA)] containing 500 uM of enzyme substrate (didecanoyl glycerol) a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/23/2017
Entry Details
US Patent

TargetDiacylglycerol O-acyltransferase 1(Mouse)
Kainos Medicine

US Patent
LigandPNGBDBM209568(US9271969, 56)
Affinity DataIC50: 50nMpH: 7.4 T: 2°CAssay Description: Assay buffer [20 mM HEPES (pH 7.4), 100 mM MgCl2 and 0.04% bovine serum albumin (BSA)] containing 500 uM of enzyme substrate (didecanoyl glycerol) a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/23/2017
Entry Details
US Patent