BDBM209931 c-Rucaparib

SMILES CN(CCCN)Cc1ccc(cc1)-c1[nH]c2cc(F)cc3C(=O)NCCc1c23

InChI Key InChIKey=NTHZKOWMZPOGQQ-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 209931   

TargetPoly [ADP-ribose] polymerase 1(Human)
H. Lee Moffitt Cancer Center & Research Institute

LigandPNGBDBM209931(c-Rucaparib)
Affinity DataIC50: 4.40nMAssay Description:Inhibition of PARP1 was assessed using the Universal Chemiluminescent PARPKit. Luminescence readings were normalized to controls and fit to a sigmoid...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/27/2017
Entry Details Article
PubMed