BDBM212244 US9290490, 2-110

SMILES COC(C)([C@H]1CC[C@@H](CC1)C(O)=O)c1ncc(s1)-c1cc(C)cc(Nc2nccc(n2)C(F)(F)F)c1

InChI Key InChIKey=DRVGGLFFFXUBGU-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 212244   

TargetTyrosine-protein kinase SYK(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM212244(US9290490, 2-110)
Affinity DataIC50: 1nMpH: 7.5 T: 2°CAssay Description:A recombinant GST-hSyk fusion protein was used to measure potency of compounds to inhibit human Syk activity. The recombinant human GST-Syk (Carna Bi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/6/2017
Entry Details
US Patent