BDBM212268 US9290490, Example 1 (slower eluting enantiomer)

SMILES Cc1cc(Nc2nccc(n2)C(F)(F)F)cc(c1)-c1cnc(s1)[C@](C)(O)[C@H]1CC[C@@H](CC1)C(O)=O

InChI Key InChIKey=MGQSNNBKPWYKBK-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 212268   

TargetTyrosine-protein kinase SYK(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM212268(US9290490, Example 1 (slower eluting enantiomer))
Affinity DataIC50: 2nMpH: 7.5 T: 2°CAssay Description:A recombinant GST-hSyk fusion protein was used to measure potency of compounds to inhibit human Syk activity. The recombinant human GST-Syk (Carna Bi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/6/2017
Entry Details
US Patent