BDBM213062 US9278960, 6-11::US9278960, 6-9::US9663506, Example 6-11

SMILES COc1ncc(Cc2ccc3c(cc(nc3c2)C(N)=O)-c2ccc(F)cc2)cn1

InChI Key InChIKey=GZWNMOXEJQPPQC-UHFFFAOYSA-N

Data  6 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 213062   

LigandPNGBDBM213062(US9278960, 6-11 | US9278960, 6-9 | US9663506, Exam...)
Affinity DataIC50: 10nMAssay Description:The utility of the compounds in accordance with the present invention as antagonists of metabotropic glutamate receptor activity, in particular mGluR...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/14/2017
Entry Details
Go to US Patent

LigandPNGBDBM213062(US9278960, 6-11 | US9278960, 6-9 | US9663506, Exam...)
Affinity DataIC50: 14nMAssay Description:The utility of the compounds in accordance with the present invention as antagonists of metabotropic glutamate receptor activity, in particular mGluR...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/14/2017
Entry Details
Go to US Patent

TargetMetabotropic glutamate receptor 2(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM213062(US9278960, 6-11 | US9278960, 6-9 | US9663506, Exam...)
Affinity DataIC50: 10nMAssay Description:The utility of the compounds in accordance with the present invention as antagonists of metabotropic glutamate receptor activity, in particular mGluR...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/29/2019
Entry Details
Go to US Patent

TargetMetabotropic glutamate receptor 2(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM213062(US9278960, 6-11 | US9278960, 6-9 | US9663506, Exam...)
Affinity DataIC50: 14nMAssay Description:The utility of the compounds in accordance with the present invention as antagonists of metabotropic glutamate receptor activity, in particular mGluR...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/29/2019
Entry Details
Go to US Patent

TargetMetabotropic glutamate receptor 2(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM213062(US9278960, 6-11 | US9278960, 6-9 | US9663506, Exam...)
Affinity DataIC50: 10nMAssay Description:The utility of the compounds in accordance with the present invention as antagonists of metabotropic glutamate receptor activity, in particular mGluR...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/4/2019
Entry Details
Go to US Patent

TargetMetabotropic glutamate receptor 2(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM213062(US9278960, 6-11 | US9278960, 6-9 | US9663506, Exam...)
Affinity DataIC50: 14nMAssay Description:The utility of the compounds in accordance with the present invention as antagonists of metabotropic glutamate receptor activity, in particular mGluR...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/4/2019
Entry Details
Go to US Patent