BDBM21366 (2-{3-[(3-fluorobenzene)sulfonyl]-1H-indol-1-yl}ethyl)dimethylamine::CHEMBL366151::flipped tryptamine derivative, 10

SMILES CN(C)CCn1cc(c2ccccc12)S(=O)(=O)c1cccc(F)c1

InChI Key InChIKey=JOERYDWTJHBWAH-UHFFFAOYSA-N

Data  3 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 21366   

Target5-hydroxytryptamine receptor 6(Human)
Wyeth Research

LigandPNGBDBM21366(CHEMBL366151 | (2-{3-[(3-fluorobenzene)sulfonyl]-1...)
Affinity DataKi:  10.3nM ΔG°:  -10.8kcal/molepH: 7.4 T: 2°CAssay Description:IC50 values for each test compound were determined from nonlinear regression analysis of data collected from ligand binding experiments. The inhibiti...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/7/2008
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 6(Human)
Wyeth Research

LigandPNGBDBM21366(CHEMBL366151 | (2-{3-[(3-fluorobenzene)sulfonyl]-1...)
Affinity DataKi:  13nMAssay Description:Displacement of radioligand from human 5-HT6 receptor expressed in HeLa cells by scintillation counterMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2016
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 6(Human)
Wyeth Research

LigandPNGBDBM21366(CHEMBL366151 | (2-{3-[(3-fluorobenzene)sulfonyl]-1...)
Affinity DataKi:  13nMAssay Description:Binding affinity against human 5-hydroxytryptamine 6 receptor transfected in HeLa cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed