BDBM21564 2-{5-chloro-1'-[(2E)-3-phenylprop-2-en-1-yl]-1,2-dihydrospiro[indole-3,3'-pyrrolidine]-2,2',5'-trione}acetic acid::Spiro-indolinone analogue, 56

SMILES OC(=O)CN1C(=O)C2(CC(=O)N(C\C=C\c3ccccc3)C2=O)c2cc(Cl)ccc12

InChI Key InChIKey=KANZJDBAFHPYNR-UHFFFAOYSA-N

Data  1 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 21564   

TargetProstaglandin D2 receptor 2(Human)
Merck Serono

LigandPNGBDBM21564(2-{5-chloro-1'-[(2E)-3-phenylprop-2-en-1-yl]-1,2-d...)
Affinity DataKi:  747nM ΔG°:  -8.27kcal/molepH: 7.4 T: 2°CAssay Description:A scintillation proximity assay was used for radioligand competition and saturation binding assays. Nonspecific binding was determined in the presenc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2008
Entry Details Article
PubMed