BDBM21815 2-[(1S)-5-(3-{4-[4-(carboxymethyl)-1,3-thiazol-2-yl]-2-propylphenoxy}propoxy)-2,3-dihydro-1H-inden-1-yl]acetic acid::Indanylacetic Acid Analog, 34ad

SMILES CCCc1cc(ccc1OCCCOc1ccc2[C@H](CC(O)=O)CCc2c1)-c1nc(CC(O)=O)cs1

InChI Key InChIKey=LMHOCAPOMOVOTR-UHFFFAOYSA-N

Data  5 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 21815   

TargetPeroxisome proliferator-activated receptor delta(Human)
Bayer Healthcare Pharmaceuticals

LigandPNGBDBM21815(2-[(1S)-5-(3-{4-[4-(carboxymethyl)-1,3-thiazol-2-y...)
Affinity DataEC50:  4.60nMT: 2°CAssay Description:Activity was assessed by measuring the human PPAR ligand binding domain with the co-activator protein. Europium labeled anti-GST antibody, streptavid...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/29/2008
Entry Details Article
PubMed
TargetPeroxisome proliferator-activated receptor gamma(Human)
Bayer Healthcare Pharmaceuticals

LigandPNGBDBM21815(2-[(1S)-5-(3-{4-[4-(carboxymethyl)-1,3-thiazol-2-y...)
Affinity DataEC50:  27nMT: 2°CAssay Description:Activity was assessed by measuring the human PPAR ligand binding domain with the co-activator protein. Europium labeled anti-GST antibody, streptavid...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/29/2008
Entry Details Article
PubMed
TargetPeroxisome proliferator-activated receptor alpha(Human)
Bayer Healthcare Pharmaceuticals

LigandPNGBDBM21815(2-[(1S)-5-(3-{4-[4-(carboxymethyl)-1,3-thiazol-2-y...)
Affinity DataEC50:  2.48E+3nMT: 2°CAssay Description:Activity was assessed by measuring the human PPAR ligand binding domain with the co-activator protein. Europium labeled anti-GST antibody, streptavid...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/29/2008
Entry Details Article
PubMed
TargetPeroxisome proliferator-activated receptor alpha(Human)
Bayer Healthcare Pharmaceuticals

LigandPNGBDBM21815(2-[(1S)-5-(3-{4-[4-(carboxymethyl)-1,3-thiazol-2-y...)
Affinity DataEC50:  4.03E+5nMAssay Description:Agonist activity at GST-tagged Homo sapiens (human) PPARalpha ligand binding domain after 2 hr by FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2020
Entry Details Article

TargetPeroxisome proliferator-activated receptor delta(Human)
Bayer Healthcare Pharmaceuticals

LigandPNGBDBM21815(2-[(1S)-5-(3-{4-[4-(carboxymethyl)-1,3-thiazol-2-y...)
Affinity DataEC50:  2.17E+8nMAssay Description:Agonist activity at GST-tagged Homo sapiens (human) PPARdelta ligand binding domain after 2 hr by FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2020
Entry Details Article