BDBM21859 1'-(4-tert-butylcyclohexyl)-2,3-dihydro-1H-spiro[isoquinoline-4,4'-piperidine]-3-one::Piperidine Derivative, 6g

SMILES CC(C)(C)C1CCC(CC1)N1CCC2(CC1)C(=O)NCc1ccccc21

InChI Key InChIKey=NKQWPIBQHVKIOM-UHFFFAOYSA-N

Data  4 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 21859   

TargetNociceptin receptor(Human)
Istituto Superiore Di Sanita

LigandPNGBDBM21859(1'-(4-tert-butylcyclohexyl)-2,3-dihydro-1H-spiro[i...)
Affinity DataKi:  42nM ΔG°:  -9.96kcal/molepH: 7.4 T: 2°CAssay Description:IC50 values were obtained by fitting the competition binding curves according to a 4-parameter logistic model. Inhibition constants Ki were derived f...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/30/2008
Entry Details Article
PubMed
TargetKappa-type opioid receptor(Human)
Istituto Superiore Di Sanita

LigandPNGBDBM21859(1'-(4-tert-butylcyclohexyl)-2,3-dihydro-1H-spiro[i...)
Affinity DataKi:  3.84E+3nMAssay Description:IC50 values were obtained by fitting the competition binding curves according to a 4-parameter logistic model. Inhibition constants Ki were derived f...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/30/2008
Entry Details Article
PubMed
TargetMu-type opioid receptor(Human)
Istituto Superiore Di Sanita

LigandPNGBDBM21859(1'-(4-tert-butylcyclohexyl)-2,3-dihydro-1H-spiro[i...)
Affinity DataKi:  6.14E+3nMAssay Description:IC50 values were obtained by fitting the competition binding curves according to a 4-parameter logistic model. Inhibition constants Ki were derived f...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/30/2008
Entry Details Article
PubMed
TargetDelta-type opioid receptor(Human)
Istituto Superiore Di Sanita

LigandPNGBDBM21859(1'-(4-tert-butylcyclohexyl)-2,3-dihydro-1H-spiro[i...)
Affinity DataKi: >1.00E+4nMAssay Description:IC50 values were obtained by fitting the competition binding curves according to a 4-parameter logistic model. Inhibition constants Ki were derived f...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/30/2008
Entry Details Article
PubMed