BDBM218808 8-[Fluo]-cAMP

SMILES Nc1ncnc2n(C3OC4COP([O-])(=O)OC4C3O)c(SCCNC(=S)Nc3ccc(c(c3)C(O)=O)-c3c4ccc(O)cc4oc4cc(=O)ccc34)nc12

InChI Key InChIKey=CQCCASCBDPGSNI-UHFFFAOYSA-M

Data  5 Kd

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 218808   

TargetcAMP-dependent protein kinase type I-alpha regulatory subunit(Human)
University of California San Diego

LigandPNGBDBM218808(8-[Fluo]-cAMP)
Affinity DataKd:  7.30nMAssay Description:The ability of the R subunit basic patch mutants to bind cAMP in the absence of the C subunit was tested using the fluorescent cAMP analogue, 8-[fluo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/22/2017
Entry Details Article
PubMed
TargetcAMP-dependent protein kinase type I-alpha regulatory subunit [R241A](Human)
University of California San Diego

LigandPNGBDBM218808(8-[Fluo]-cAMP)
Affinity DataKd:  6.72nMAssay Description:The ability of the R subunit basic patch mutants to bind cAMP in the absence of the C subunit was tested using the fluorescent cAMP analogue, 8-[fluo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/22/2017
Entry Details Article
PubMed
TargetcAMP-dependent protein kinase type I-alpha regulatory subunit [K242A](Human)
University of California San Diego

LigandPNGBDBM218808(8-[Fluo]-cAMP)
Affinity DataKd:  7.32nMAssay Description:The ability of the R subunit basic patch mutants to bind cAMP in the absence of the C subunit was tested using the fluorescent cAMP analogue, 8-[fluo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/22/2017
Entry Details Article
PubMed
TargetcAMP-dependent protein kinase type I-alpha regulatory subunit [R243A](Human)
University of California San Diego

LigandPNGBDBM218808(8-[Fluo]-cAMP)
Affinity DataKd:  7.29nMAssay Description:The ability of the R subunit basic patch mutants to bind cAMP in the absence of the C subunit was tested using the fluorescent cAMP analogue, 8-[fluo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/22/2017
Entry Details Article
PubMed
TargetcAMP-dependent protein kinase type I-alpha regulatory subunit [K244A](Human)
University of California San Diego

LigandPNGBDBM218808(8-[Fluo]-cAMP)
Affinity DataKd:  7.71nMAssay Description:The ability of the R subunit basic patch mutants to bind cAMP in the absence of the C subunit was tested using the fluorescent cAMP analogue, 8-[fluo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/22/2017
Entry Details Article
PubMed