BDBM21965 3-[(4S,6S)-4-amino-6,9-dihydroxynonyl]-1-nitroguanidine::Hydroxyethylene derivative, 4

SMILES N[C@@H](CCCN=C(N)N[N+]([O-])=O)C[C@@H](O)CCCO

InChI Key InChIKey=LDVMACANLGUJCA-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 21965   

TargetNitric oxide synthase, brain(Rat)
Northwestern University

LigandPNGBDBM21965(3-[(4S,6S)-4-amino-6,9-dihydroxynonyl]-1-nitroguan...)
Affinity DataIC50: 2.55E+5nMpH: 7.4 T: 2°CAssay Description:Nitric oxide formation from NOS was monitored by the hemoglobin capture assay. The assay was initiated by addition of enzyme and was monitored at 401...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/30/2008
Entry Details Article
PubMed
TargetNitric oxide synthase, endothelial(Bovine)
Northwestern University

LigandPNGBDBM21965(3-[(4S,6S)-4-amino-6,9-dihydroxynonyl]-1-nitroguan...)
Affinity DataIC50: 2.58E+6nMpH: 7.4 T: 2°CAssay Description:Nitric oxide formation from NOS was monitored by the hemoglobin capture assay. The assay was initiated by addition of enzyme and was monitored at 401...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/30/2008
Entry Details Article
PubMed
TargetNitric oxide synthase, inducible(Mouse)
Northwestern University

LigandPNGBDBM21965(3-[(4S,6S)-4-amino-6,9-dihydroxynonyl]-1-nitroguan...)
Affinity DataIC50: 5.24E+5nMpH: 7.4 T: 2°CAssay Description:Nitric oxide formation from NOS was monitored by the hemoglobin capture assay. The assay was initiated by addition of enzyme and was monitored at 401...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/30/2008
Entry Details Article
PubMed