BDBM22133 aza-peptide Michael acceptor, 7e::benzyl N-[(1S)-1-{[(1S)-1-[N'-(carbamoylmethyl)-N'-[(2E)-3-(furan-2-yl)prop-2-enoyl]hydrazinecarbonyl]ethyl]carbamoyl}ethyl]carbamate

SMILES C[C@H](NC(=O)OCc1ccccc1)C(=O)N[C@@H](C)C(=O)NN(CC(N)=O)C(=O)C=Cc1ccco1

InChI Key InChIKey=STHFKBYGYCNCEA-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 22133   

TargetLegumain(Blood fluke)
Georgia Institute of Technology

LigandPNGBDBM22133(benzyl N-[(1S)-1-{[(1S)-1-[N'-(carbamoylmethyl)-N'...)
Affinity DataIC50: 2.00E+3nMpH: 6.8 T: 2°CAssay Description:AE activity in the induction medium was measured with the substrate Cbz-Ala-Ala-Asn-AMC. In a black 96-well microtiter plate, aza-peptidyl inhibitors...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/9/2008
Entry Details Article
PubMed
TargetLegumain(Common tick)
Georgia Institute of Technology

LigandPNGBDBM22133(benzyl N-[(1S)-1-{[(1S)-1-[N'-(carbamoylmethyl)-N'...)
Affinity DataIC50: 7.50E+3nMT: 2°CAssay Description:AE activity in the induction medium was measured with the substrate Cbz-Ala-Ala-Asn-AMC. In a black 96-well microtiter plate, aza-peptidyl inhibitors...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/9/2008
Entry Details Article
PubMed