BDBM222019 N-((1-(2-chlorobenzyl)-1H-1,2,3-triazol-4-yl)methyl)-8-methoxy-2-oxo-2H-chromene-3-carboxamide (6m)

SMILES COc1cccc2cc(C(=O)NCc3cn(Cc4ccccc4Cl)nn3)c(=O)oc12

InChI Key InChIKey=RUWYNMDMMZCOHP-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 222019   

TargetAcetylcholinesterase(Electric eel)
Tehran University of Medical Sciences

LigandPNGBDBM222019(N-((1-(2-chlorobenzyl)-1H-1,2,3-triazol-4-yl)methy...)
Affinity DataIC50: 1.54E+4nMpH: 8.0 T: 2°CAssay Description:In vitro anti-AChE activity was performed based on the modified Ellman's method [Ellman et al., Biochem. Pharmacol., 71:88-95]. For this purpose, syn...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/11/2017
Entry Details Article
PubMed
TargetCarboxylic ester hydrolase(Horse)
Tehran University of Medical Sciences

LigandPNGBDBM222019(N-((1-(2-chlorobenzyl)-1H-1,2,3-triazol-4-yl)methy...)
Affinity DataIC50: 9.61E+4nMpH: 8.0 T: 2°CAssay Description:In vitro anti-AChE activity was performed based on the modified Ellman's method [Ellman et al., Biochem. Pharmacol., 71:88-95]. For this purpose, syn...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/11/2017
Entry Details Article
PubMed
TargetAcetylcholinesterase(Electric eel)
Tehran University of Medical Sciences

LigandPNGBDBM222019(N-((1-(2-chlorobenzyl)-1H-1,2,3-triazol-4-yl)methy...)
Affinity DataIC50: 1.54E+4nMAssay Description:Inhibition of electric eel AChE using acetylthiocholine iodide as substrate preincubated for 15 mins followed by substrate addition and measured afte...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/24/2021
Entry Details Article
PubMed