BDBM222145 2-(4-chlorophenyl)-2-methyl-2,3-dihydroquinazolin-4(1H)-one (3f)

SMILES CC1(NC(=O)c2ccccc2N1)c1ccc(Cl)cc1

InChI Key InChIKey=JVNNEQAYIKZACR-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 222145   

TargetAcetylcholinesterase(Electric eel)
University of Sargodha

LigandPNGBDBM222145(2-(4-chlorophenyl)-2-methyl-2,3-dihydroquinazolin-...)
Affinity DataIC50: 9.90E+3nMpH: 8.0Assay Description:Galantamine was used as reference drugs. The synthesized quinazolines were dissolved in 0.1 M phosphate buffer of pH 8.0. (KH2PO4/K2HPO4. The reactio...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2017
Entry Details Article
PubMed
TargetCarboxylic ester hydrolase(Horse)
University of Sargodha

LigandPNGBDBM222145(2-(4-chlorophenyl)-2-methyl-2,3-dihydroquinazolin-...)
Affinity DataIC50: 1.12E+4nMpH: 8.0Assay Description:Galantamine was used as reference drugs. The synthesized quinazolines were dissolved in 0.1 M phosphate buffer of pH 8.0. (KH2PO4/K2HPO4. The reactio...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2017
Entry Details Article
PubMed