BDBM22244 2,4,5-tri-substituted imidazole, 14i::N-{2-[5-(4-methoxyphenyl)-2-(pyridin-4-yl)-1H-imidazol-4-yl]ethyl}-4-pentylbenzene-1-sulfonamide

SMILES CCCCCc1ccc(cc1)S(=O)(=O)NCCc1[nH]c(nc1-c1ccc(OC)cc1)-c1ccncc1

InChI Key InChIKey=IERMWUNTRGAXSX-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 22244   

TargetPolyunsaturated fatty acid lipoxygenase ALOX15(Rabbit)
Bristol-Myers Squibb

LigandPNGBDBM22244(N-{2-[5-(4-methoxyphenyl)-2-(pyridin-4-yl)-1H-imid...)
Affinity DataIC50: 87nMAssay Description:The inhibitory activity of the compounds against purified 15-LO enzyme was determined using a standard colorimetric assay in which the lipid hydroper...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/28/2008
Entry Details Article
PubMed