BDBM222451 N-(4-((2-(4-ethylpiperazine-1-carbonyl) pyridin-4-yl) oxy-3-fluorophenyl)-1,5-dimethyl-3-oxo-2-phenyl-2,3-dihydro-1H-pyrazole-4-carboxamide (9j)

SMILES CCN1CCN(CC1)C(=O)c1cc(Oc2ccc(NC(=O)c3c(C)n(C)n(-c4ccccc4)c3=O)cc2F)ccn1

InChI Key InChIKey=UQWYNGLUPIBCGC-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 222451   

TargetHepatocyte growth factor receptor(Human)
China Pharmaceutical University

LigandPNGBDBM222451(N-(4-((2-(4-ethylpiperazine-1-carbonyl) pyridin-4-...)
Affinity DataIC50: 970nMpH: 7.4 T: 2°CAssay Description:Briefly, 20 μg/mL poly (Glu,Tyr) 4:1 (Sigma) was pre-coated in 96-well plates as a substrate. A 50 μL aliquot of 10 μmol/L ATP solutio...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2017
Entry Details Article
PubMed
TargetVascular endothelial growth factor receptor 2(Human)
China Pharmaceutical University

LigandPNGBDBM222451(N-(4-((2-(4-ethylpiperazine-1-carbonyl) pyridin-4-...)
Affinity DataIC50: 1.00E+3nMpH: 7.4 T: 2°CAssay Description:Briefly, 20 μg/mL poly (Glu,Tyr) 4:1 (Sigma) was pre-coated in 96-well plates as a substrate. A 50 μL aliquot of 10 μmol/L ATP solutio...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2017
Entry Details Article
PubMed