BDBM222453 N-(4-((2-([1,4'-bipiperidine]-1'-carbonyl) pyridin-4-yl) oxy)-3-fluorophenyl)-1,5-dimethyl-3-oxo-2-phenyl-2,3-dihydro-1H-pyrazole-4-carboxamide (9o)

SMILES Cc1c(C(=O)Nc2ccc(Oc3ccnc(c3)C(=O)N3CCC(CC3)N3CCCCC3)c(F)c2)c(=O)n(-c2ccccc2)n1C

InChI Key InChIKey=YUEIVZVKVPTLKP-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 222453   

TargetHepatocyte growth factor receptor(Human)
China Pharmaceutical University

LigandPNGBDBM222453(N-(4-((2-([1,4'-bipiperidine]-1'-carbonyl)...)
Affinity DataIC50: 330nMpH: 7.4 T: 2°CAssay Description:Briefly, 20 μg/mL poly (Glu,Tyr) 4:1 (Sigma) was pre-coated in 96-well plates as a substrate. A 50 μL aliquot of 10 μmol/L ATP solutio...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2017
Entry Details Article
PubMed
TargetVascular endothelial growth factor receptor 2(Human)
China Pharmaceutical University

LigandPNGBDBM222453(N-(4-((2-([1,4'-bipiperidine]-1'-carbonyl)...)
Affinity DataIC50: 780nMpH: 7.4 T: 2°CAssay Description:Briefly, 20 μg/mL poly (Glu,Tyr) 4:1 (Sigma) was pre-coated in 96-well plates as a substrate. A 50 μL aliquot of 10 μmol/L ATP solutio...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2017
Entry Details Article
PubMed