BDBM222454 N-(3-fluoro-4-((2-(4-(3-dimethylaminopropyl)-4H-1,2,4-triazol-3-yl) pyridin-4-yl) oxy)phenyl)-1,5-dimethyl-3-oxo-2-phenyl-2,3-dihydro-1H-pyrazole-4-carboxamide (12b)

SMILES CN(C)CCCn1cnnc1-c1cc(Oc2ccc(NC(=O)c3c(C)n(C)n(-c4ccccc4)c3=O)cc2F)ccn1

InChI Key InChIKey=NKANTOLWUPJONB-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 222454   

TargetHepatocyte growth factor receptor(Human)
China Pharmaceutical University

LigandPNGBDBM222454(N-(3-fluoro-4-((2-(4-(3-dimethylaminopropyl)-4H-1,...)
Affinity DataIC50: 150nMpH: 7.4 T: 2°CAssay Description:Briefly, 20 μg/mL poly (Glu,Tyr) 4:1 (Sigma) was pre-coated in 96-well plates as a substrate. A 50 μL aliquot of 10 μmol/L ATP solutio...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2017
Entry Details Article
PubMed
TargetVascular endothelial growth factor receptor 2(Human)
China Pharmaceutical University

LigandPNGBDBM222454(N-(3-fluoro-4-((2-(4-(3-dimethylaminopropyl)-4H-1,...)
Affinity DataIC50: 370nMpH: 7.4 T: 2°CAssay Description:Briefly, 20 μg/mL poly (Glu,Tyr) 4:1 (Sigma) was pre-coated in 96-well plates as a substrate. A 50 μL aliquot of 10 μmol/L ATP solutio...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2017
Entry Details Article
PubMed