BDBM222459 (E)-4-[2-(4-Chlorophenyl)-4-(2,3-dimethoxybenzylidene)-5-oxo-4,5-dihydroimidazol-1-yl]-benzenesulfonamide (10c)

SMILES COc1cccc(\C=C2\N=C(N(C2=O)c2ccc(cc2)S(N)(=O)=O)c2ccc(Cl)cc2)c1OC

InChI Key InChIKey=RYAFMHBMMWNSFD-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 222459   

TargetProstaglandin G/H synthase 2(Human)
Beni-Suef University

LigandPNGBDBM222459((E)-4-[2-(4-Chlorophenyl)-4-(2,3-dimethoxybenzylid...)
Affinity DataIC50: 920nMAssay Description:The ability of the test compounds 10a-h listed in Table 1 to inhibit ovine COX-1 and human recombinant COX-2 (IC50 value, mM) was determined using an...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2017
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 1(Sheep)
Beni-Suef University

LigandPNGBDBM222459((E)-4-[2-(4-Chlorophenyl)-4-(2,3-dimethoxybenzylid...)
Affinity DataIC50: 6.28E+3nMAssay Description:The ability of the test compounds 10a-h listed in Table 1 to inhibit ovine COX-1 and human recombinant COX-2 (IC50 value, mM) was determined using an...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2017
Entry Details Article
PubMed