BDBM222463 (E)-4-[4-(4-Chlorobenzylidene)-2-(4-chlorophenyl)-5-oxo-4,5-dihydroimidazol-1-yl]-benzene-sulfonamide (10g)

SMILES NS(=O)(=O)c1ccc(cc1)N1C(=O)\C(=C/c2ccc(Cl)cc2)N=C1c1ccc(Cl)cc1

InChI Key InChIKey=BOQZBNGIJCPYSZ-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 222463   

TargetProstaglandin G/H synthase 1(Sheep)
Beni-Suef University

LigandPNGBDBM222463((E)-4-[4-(4-Chlorobenzylidene)-2-(4-chlorophenyl)-...)
Affinity DataIC50: 8.62E+3nMAssay Description:The ability of the test compounds 10a-h listed in Table 1 to inhibit ovine COX-1 and human recombinant COX-2 (IC50 value, mM) was determined using an...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2017
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 2(Human)
Beni-Suef University

LigandPNGBDBM222463((E)-4-[4-(4-Chlorobenzylidene)-2-(4-chlorophenyl)-...)
Affinity DataIC50: 1.14E+3nMAssay Description:The ability of the test compounds 10a-h listed in Table 1 to inhibit ovine COX-1 and human recombinant COX-2 (IC50 value, mM) was determined using an...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2017
Entry Details Article
PubMed