BDBM222542 US9315489, 78

SMILES Fc1cncc(c1)-c1cc(cnc1Cl)C(=O)Nc1ccc(OC(F)(F)Cl)cc1

InChI Key InChIKey=CMRMYCHYPFVHEO-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 222542   

TargetTyrosine-protein kinase ABL1 [64-515](Human)
Novartis

US Patent
LigandPNGBDBM222542(US9315489, 78)
Affinity DataIC50: 3.90nMpH: 7.5 T: 2°CAssay Description:All assays were performed in 384-well microtiter plates. Each assay plate contained 8-point serial dilutions for 40 test compounds, as well as four 8...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/24/2017
Entry Details
Go to US Patent