BDBM223004 US10034939, Example 6::US10967060, Example 6::US11207302, Example 6::US9320732, 6

SMILES CS(=O)(=O)NCCNc1nonc1C(Nc1ccc(F)c(Cl)c1)=NO

InChI Key InChIKey=WIHANXODBMGZHO-UHFFFAOYSA-N

Data  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 223004   

TargetIndoleamine 2,3-dioxygenase 1(Human)
Incyte

US Patent
LigandPNGBDBM223004(US9320732, 6 | US10034939, Example 6 | US10967060,...)
Affinity DataIC50: 200nMpH: 6.5 T: 2°CAssay Description:Human indoleamine 2,3-dioxygenasae (IDO) with an N-terminal His tag was expressed in E. coli and purified to homogeneity. IDO catalyzes the oxidative...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/24/2017
Entry Details
Go to US Patent

TargetIndoleamine 2,3-dioxygenase 1(Human)
Incyte

US Patent
LigandPNGBDBM223004(US9320732, 6 | US10034939, Example 6 | US10967060,...)
Affinity DataIC50: 200nMpH: 6.5 T: 2°CAssay Description:Human indoleamine 2,3-dioxygenasae (IDO) with an N-terminal His tag was expressed in E. coli and purified to homogeneity. IDO catalyzes the oxidative...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/25/2018
Entry Details
Go to US Patent

TargetIndoleamine 2,3-dioxygenase 1(Human)
Incyte

US Patent
LigandPNGBDBM223004(US9320732, 6 | US10034939, Example 6 | US10967060,...)
Affinity DataIC50: 200nMpH: 6.5 T: 2°CAssay Description:Human indoleamine 2,3-dioxygenasae (IDO) with an N-terminal His tag was expressed in E. coli and purified to homogeneity. IDO catalyzes the oxidative...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/25/2018
Entry Details
Go to US Patent

TargetIndoleamine 2,3-dioxygenase 1(Human)
Incyte

US Patent
LigandPNGBDBM223004(US9320732, 6 | US10034939, Example 6 | US10967060,...)
Affinity DataIC50: 200nMAssay Description:Human indoleamine 2,3-dioxygenasae (IDO) with an N-terminal His tag was expressed in E. coli and purified to homogeneity. IDO catalyzes the oxidative...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/9/2021
Entry Details
Go to US Patent

TargetIndoleamine 2,3-dioxygenase 1(Human)
Incyte

US Patent
LigandPNGBDBM223004(US9320732, 6 | US10034939, Example 6 | US10967060,...)
Affinity DataIC50: 200nMAssay Description:Human indoleamine 2,3-dioxygenasae (IDO) with an N-terminal His tag was expressed in E. coli and purified to homogeneity. IDO catalyzes the oxidative...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/2/2022
Entry Details
Go to US Patent