BDBM223014 US10034939, Example 16::US10967060, Example 16::US11207302, Example 16::US9320732, 16::US9789094, 16

SMILES CS(=O)(=O)NCCCNc1nonc1C(Nc1cccc(c1)C(F)(F)F)=NO

InChI Key InChIKey=NQNWGOYDURQABD-UHFFFAOYSA-N

Data  6 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 223014   

TargetIndoleamine 2,3-dioxygenase 1(Human)
Incyte

US Patent
LigandPNGBDBM223014(US9320732, 16 | US10034939, Example 16 | US9789094...)
Affinity DataIC50: 200nMpH: 6.5 T: 2°CAssay Description:Human indoleamine 2,3-dioxygenasae (IDO) with an N-terminal His tag was expressed in E. coli and purified to homogeneity. IDO catalyzes the oxidative...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/24/2017
Entry Details
Go to US Patent

TargetIndoleamine 2,3-dioxygenase 1(Human)
Incyte

US Patent
LigandPNGBDBM223014(US9320732, 16 | US10034939, Example 16 | US9789094...)
Affinity DataIC50: 200nMpH: 6.5 T: 2°CAssay Description:Human indoleamine 2,3-dioxygenasae (IDO) with an N-terminal His tag was expressed in E. coli and purified to homogeneity. IDO catalyzes the oxidative...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/25/2018
Entry Details
Go to US Patent

TargetIndoleamine 2,3-dioxygenase 1(Human)
Incyte

US Patent
LigandPNGBDBM223014(US9320732, 16 | US10034939, Example 16 | US9789094...)
Affinity DataIC50: 200nMpH: 6.5 T: 2°CAssay Description:Human indoleamine 2,3-dioxygenasae (IDO) with an N-terminal His tag was expressed in E. coli and purified to homogeneity. IDO catalyzes the oxidative...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/25/2018
Entry Details
Go to US Patent

TargetIndoleamine 2,3-dioxygenase 1(Human)
Incyte

US Patent
LigandPNGBDBM223014(US9320732, 16 | US10034939, Example 16 | US9789094...)
Affinity DataIC50: 200nMAssay Description:Human indoleamine 2,3-dioxygenasae (IDO) with an N-terminal His tag was expressed in E. coli and purified to homogeneity. IDO catalyzes the oxidative...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/9/2019
Entry Details
Go to US Patent

TargetIndoleamine 2,3-dioxygenase 1(Human)
Incyte

US Patent
LigandPNGBDBM223014(US9320732, 16 | US10034939, Example 16 | US9789094...)
Affinity DataIC50: 200nMAssay Description:Human indoleamine 2,3-dioxygenasae (IDO) with an N-terminal His tag was expressed in E. coli and purified to homogeneity. IDO catalyzes the oxidative...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/9/2021
Entry Details
Go to US Patent

TargetIndoleamine 2,3-dioxygenase 1(Human)
Incyte

US Patent
LigandPNGBDBM223014(US9320732, 16 | US10034939, Example 16 | US9789094...)
Affinity DataIC50: 200nMAssay Description:Human indoleamine 2,3-dioxygenasae (IDO) with an N-terminal His tag was expressed in E. coli and purified to homogeneity. IDO catalyzes the oxidative...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/2/2022
Entry Details
Go to US Patent