BDBM22331 2-amino-5-hydroxyindole, 3m::ethyl 2-[bis(prop-2-en-1-yl)amino]-5-hydroxy-1H-indole-3-carboxylate

SMILES CCOC(=O)c1c([nH]c2ccc(O)cc12)N(CC=C)CC=C

InChI Key InChIKey=RRXOJFSNCYSTNB-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 22331   

TargetPolyunsaturated fatty acid 5-lipoxygenase(Human)
Friedrich Alexander University Erlangen

LigandPNGBDBM22331(ethyl 2-[bis(prop-2-en-1-yl)amino]-5-hydroxy-1H-in...)
Affinity DataIC50: 7.10E+3nMpH: 7.4 T: 2°CAssay Description:Purified 5-LO was added to reaction mix containing the test compounds. For efficient inhibition of 5-LO, low hydroperoxide levels are important. Glut...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/31/2008
Entry Details Article
PubMed