BDBM22454 2-Amino-1,3-thiazol-4(5H)-one, 5b::2-[(cyclohexylmethyl)amino]-5-ethyl-5-methyl-4,5-dihydro-1,3-thiazol-4-one

SMILES CCC1(C)SC(NCC2CCCCC2)=NC1=O

InChI Key InChIKey=GTQGEQUWUJUZPN-UHFFFAOYSA-N

Data  1 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 22454   

LigandPNGBDBM22454(2-[(cyclohexylmethyl)amino]-5-ethyl-5-methyl-4,5-d...)
Affinity DataKi:  64nM ΔG°:  -9.71kcal/molepH: 7.2 T: 2°CAssay Description:The 11beta-HSD1 enzyme assay was carried out in the replica plates of the compounds in reaction buffer containing substrate mixture [3H]-cortisone/NA...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/30/2008
Entry Details Article
PubMed