BDBM22457 2-(cycloheptylamino)-5-methyl-5-propyl-4,5-dihydro-1,3-thiazol-4-one::2-Amino-1,3-thiazol-4(5H)-one, 6c

SMILES CCCC1(C)SC(NC2CCCCCC2)=NC1=O

InChI Key InChIKey=PQXVEAATFKMFDU-UHFFFAOYSA-N

Data  1 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 22457   

LigandPNGBDBM22457(2-(cycloheptylamino)-5-methyl-5-propyl-4,5-dihydro...)
Affinity DataKi:  32nM ΔG°:  -10.1kcal/molepH: 7.2 T: 2°CAssay Description:The 11beta-HSD1 enzyme assay was carried out in the replica plates of the compounds in reaction buffer containing substrate mixture [3H]-cortisone/NA...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/30/2008
Entry Details Article
PubMed
LigandPNGBDBM22457(2-(cycloheptylamino)-5-methyl-5-propyl-4,5-dihydro...)
Affinity DataIC50: 1.00E+4nMAssay Description:The 11beta-HSD1 enzyme assay was carried out in the replica plates of the compounds in reaction buffer containing substrate mixture [3H]-cortisone/NA...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/30/2008
Entry Details Article
PubMed