BDBM22474 2-(adamantan-1-ylamino)-5,5-diethyl-4,5-dihydro-1,3-thiazol-4-one::2-Amino-1,3-thiazol-4(5H)-one, 7c

SMILES CCC1(CC)SC(NC23CC4CC(CC(C4)C2)C3)=NC1=O

InChI Key

Data  1 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 22474   

LigandPNGBDBM22474(2-(adamantan-1-ylamino)-5,5-diethyl-4,5-dihydro-1,...)
Affinity DataKi:  20nM ΔG°:  -10.4kcal/molepH: 7.2 T: 2°CAssay Description:The 11beta-HSD1 enzyme assay was carried out in the replica plates of the compounds in reaction buffer containing substrate mixture [3H]-cortisone/NA...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/30/2008
Entry Details Article
PubMed