BDBM22475 2-(adamantan-1-ylamino)-1-thia-3-azaspiro[4.4]non-2-en-4-one::2-Amino-1,3-thiazol-4(5H)-one, 8c

SMILES O=C1N=C(NC23CC4CC(CC(C4)C2)C3)SC11CCCC1

InChI Key

Data  1 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 22475   

LigandPNGBDBM22475(2-(adamantan-1-ylamino)-1-thia-3-azaspiro[4.4]non-...)
Affinity DataKi:  28nM ΔG°:  -10.2kcal/molepH: 7.2 T: 2°CAssay Description:The 11beta-HSD1 enzyme assay was carried out in the replica plates of the compounds in reaction buffer containing substrate mixture [3H]-cortisone/NA...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/30/2008
Entry Details Article
PubMed