BDBM225237 BTK inhibitor, 2

SMILES CNC(=O)Cc1cccc(NC(=O)c2n[nH]cc2CNc2ccccc2[C@H](O)c2ccccc2)c1

InChI Key InChIKey=XOJRDJPXNUBFEM-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 225237   

TargetTyrosine-protein kinase BTK(Human)
X-Chem Pharmaceuticals

LigandPNGBDBM225237(BTK inhibitor, 2)
Affinity DataIC50: 210nMT: 2°CAssay Description:The BTK time-resolved FRET-based competitive binding assay and cell-based BTK assays have been previously described.[Xu et al., J.Pharmacol. Exp. The...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/9/2017
Entry Details Article
PubMed