BDBM22553 2-[3-(1H-imidazol-4-ylmethyl)phenyl]-5,5-dimethyl-5,6-dihydro-4H-1,3-oxazine::4-Benzyl-1H-imidazole derivative, 31

SMILES CC1(C)COC(=NC1)c1cccc(Cc2cnc[nH]2)c1

InChI Key InChIKey=ZPBNADIRZNHTBQ-UHFFFAOYSA-N

Data  1 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 22553   

TargetHistamine H3 receptor(Human)
Vu University Amsterdam

LigandPNGBDBM22553(2-[3-(1H-imidazol-4-ylmethyl)phenyl]-5,5-dimethyl-...)
Affinity DataKi:  2.51E+3nM ΔG°:  -7.63kcal/molepH: 7.4 T: 2°CAssay Description:Ligand displacement assays were performed on CHO cells membranes expressing hH3R. Retained radioactivity was determined by liquid scintillation count...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/13/2008
Entry Details Article
PubMed