BDBM22609 JMC496646 Compound 14::N-[(4-fluorophenyl)methyl]-5,6-dihydroxy-2-(1-methylpiperidin-2-yl)pyrimidine-4-carboxamide::dihydroxypyrimidine deriv., 9

SMILES CN1CCCCC1c1nc(C(=O)NCc2ccc(F)cc2)c(O)c(=O)[nH]1

InChI Key InChIKey=KPXYCCGYCRCUCJ-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 22609   

TargetGag-Pol polyprotein(HIV-1)
Irbm-Mrl

LigandPNGBDBM22609(JMC496646 Compound 14 | N-[(4-fluorophenyl)methyl]...)
Affinity DataIC50: 220nMpH: 7.8 T: 2°CAssay Description:The microtiter plate assay for stand transfer was performed with an immobilized donor substrate and a target substrate biotinylated at the 3-prime en...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/15/2008
Entry Details Article
PubMed
TargetGag-Pol polyprotein(HIV-1)
Irbm-Mrl

LigandPNGBDBM22609(JMC496646 Compound 14 | N-[(4-fluorophenyl)methyl]...)
Affinity DataIC50: 200nMpH: 7.8 T: 2°CAssay Description:The microtiter plate assay for stand transfer was performed with an immobilized donor substrate and a target substrate biotinylated at the 3-prime en...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/15/2008
Entry Details Article
PubMed