BDBM22618 N-Me-pyrimidone deriv., 17::N-[(4-fluorophenyl)methyl]-5-hydroxy-2-[(2S,4R)-4-methoxy-1-methylpyrrolidin-2-yl]-1-methyl-6-oxo-1,6-dihydropyrimidine-4-carboxamide

SMILES CO[C@@H]1C[C@H](N(C)C1)c1nc(C(=O)NCc2ccc(F)cc2)c(O)c(=O)n1C

InChI Key InChIKey=PZJGDNRDXHDJEG-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 22618   

TargetGag-Pol polyprotein(HIV-1)
Irbm-Mrl

LigandPNGBDBM22618(N-[(4-fluorophenyl)methyl]-5-hydroxy-2-[(2S,4R)-4-...)
Affinity DataIC50: 180nMpH: 7.8 T: 2°CAssay Description:The microtiter plate assay for stand transfer was performed with an immobilized donor substrate and a target substrate biotinylated at the 3-prime en...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/15/2008
Entry Details Article
PubMed