BDBM22622 2-[(2S,4S)-4-acetamido-1-methylpyrrolidin-2-yl]-N-[(4-fluorophenyl)methyl]-5-hydroxy-1-methyl-6-oxo-1,6-dihydropyrimidine-4-carboxamide::N-Me-pyrimidone deriv., 21

SMILES CN1C[C@H](C[C@H]1c1nc(C(=O)NCc2ccc(F)cc2)c(O)c(=O)n1C)NC(C)=O

InChI Key InChIKey=OMKREFWTGHIBIS-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 22622   

TargetGag-Pol polyprotein(HIV-1)
Irbm-Mrl

LigandPNGBDBM22622(2-[(2S,4S)-4-acetamido-1-methylpyrrolidin-2-yl]-N-...)
Affinity DataIC50: 61nMpH: 7.8 T: 2°CAssay Description:The microtiter plate assay for stand transfer was performed with an immobilized donor substrate and a target substrate biotinylated at the 3-prime en...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/15/2008
Entry Details Article
PubMed