BDBM22628 JMC51861 Compound 4::N-Me-pyrimidone deriv., 27::N-Methylpyrimidone, 17::N-[(4-fluorophenyl)methyl]-5-hydroxy-1-methyl-2-(3-methyl-1,3-oxazinan-2-yl)-6-oxo-1,6-dihydropyrimidine-4-carboxamide::N-[(4-fluorophenyl)methyl]-5-hydroxy-1-methyl-2-(4-methylmorpholin-3-yl)-6-oxo-1,6-dihydropyrimidine-4-carboxamide

SMILES CN1CCOCC1c1nc(C(=O)NCc2ccc(F)cc2)c(O)c(=O)n1C

InChI Key InChIKey=MMPZNODECHHWIW-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 22628   

TargetGag-Pol polyprotein(HIV-1)
Irbm-Mrl

LigandPNGBDBM22628(N-[(4-fluorophenyl)methyl]-5-hydroxy-1-methyl-2-(3...)
Affinity DataIC50: 60nMpH: 7.8 T: 2°CAssay Description:The microtiter plate assay for stand transfer was performed with an immobilized donor substrate and a target substrate biotinylated at the 3-prime en...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/15/2008
Entry Details Article
PubMed
TargetGag-Pol polyprotein(HIV-1)
Irbm-Mrl

LigandPNGBDBM22628(N-[(4-fluorophenyl)methyl]-5-hydroxy-1-methyl-2-(3...)
Affinity DataIC50: 60nMpH: 7.8 T: 2°CAssay Description:The microtiter plate assay for stand transfer was performed with an immobilized donor substrate and a target substrate biotinylated at the 3-prime en...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/15/2008
Entry Details Article
PubMed
TargetGag-Pol polyprotein(HIV-1)
Irbm-Mrl

LigandPNGBDBM22628(N-[(4-fluorophenyl)methyl]-5-hydroxy-1-methyl-2-(3...)
Affinity DataIC50: 60nMpH: 7.8 T: 2°CAssay Description:The microtiter plate assay for stand transfer was performed with an immobilized donor substrate and a target substrate biotinylated at the 3-prime en...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/15/2008
Entry Details Article
PubMed