BDBM226383 US9328096, 76

SMILES NC(=O)c1cc(NC(=O)c2cc(ccc2Cl)-c2cccc(n2)C(N)=O)n(n1)-c1ccccc1

InChI Key InChIKey=VXLKAHXNBSRIAM-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 226383   

LigandPNGBDBM226383(US9328096, 76)
Affinity DataIC50: 5.00E+4nMT: 2°CAssay Description:TRKA co-expressed with p75: The assays are based upon DiscoveRx's proprietary Enzyme Fragment Complementation (EFC) technology. In the case of the TR...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/15/2017
Entry Details
Go to US Patent

LigandPNGBDBM226383(US9328096, 76)
Affinity DataIC50: 5.00E+4nMAssay Description:Antagonist activity at prolink-tagged TrkA (unknown origin) expressed in cells assessed as inhibition of NGF-induced receptor phosphorylation by meas...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/18/2021
Entry Details Article
PubMed