BDBM22640 2-(4-benzoyl-1-methylpiperazin-2-yl)-N-[(4-fluorophenyl)methyl]-5-hydroxy-1-methyl-6-oxo-1,6-dihydropyrimidine-4-carboxamide::N-Me-pyrimidone deriv., 39

SMILES CN1CCN(CC1c1nc(C(=O)NCc2ccc(F)cc2)c(O)c(=O)n1C)C(=O)c1ccccc1

InChI Key InChIKey=BMTUWFRODUAELZ-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 22640   

TargetGag-Pol polyprotein(HIV-1)
Irbm-Mrl

LigandPNGBDBM22640(2-(4-benzoyl-1-methylpiperazin-2-yl)-N-[(4-fluorop...)
Affinity DataIC50: 12nMAssay Description:The microtiter plate assay for stand transfer was performed with an immobilized donor substrate and a target substrate biotinylated at the 3-prime en...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/15/2008
Entry Details Article
PubMed