BDBM22760 2-hydroxy-1,2-bis(4-methoxyphenyl)ethan-1-one::Benzil-related compound, 38

SMILES COc1ccc(cc1)C(O)C(=O)c1ccc(OC)cc1

InChI Key InChIKey=LRRQSCPPOIUNGX-UHFFFAOYSA-N

Data  5 KI  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 7 hits for monomerid = 22760   

TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform(Human)
Al-Zaytoonah University of Jordan

Curated by ChEMBL
LigandPNGBDBM22760(2-hydroxy-1,2-bis(4-methoxyphenyl)ethan-1-one | Be...)
Affinity DataIC50: 1.17E+6nMAssay Description:Inhibition of PI3Kalpha H1047R mutant in human HCT116 cells assessed as cell growth inhibition after 24 hrs by MTT assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/13/2016
Entry Details Article
PubMed
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform(Human)
Al-Zaytoonah University of Jordan

Curated by ChEMBL
LigandPNGBDBM22760(2-hydroxy-1,2-bis(4-methoxyphenyl)ethan-1-one | Be...)
Affinity DataIC50: 1.17E+6nMAssay Description:Inhibition of PI3Kalpha in human HCT116 cells assessed as cell growth inhibition after 24 hrs by MTT assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/13/2016
Entry Details Article
PubMed
TargetLiver carboxylesterase 1(Rabbit)
University of Mississippi

LigandPNGBDBM22760(2-hydroxy-1,2-bis(4-methoxyphenyl)ethan-1-one | Be...)
Affinity DataKi:  1.39E+4nMAssay Description:CE inhibition was determined using a spectrophotometric multiwell plate assay with o-NPA as a substrate. The rate of change in absorbance at 420 nm w...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/15/2008
Entry Details Article
PubMed
TargetCoagulation factor XII(Human)
University of Mississippi

LigandPNGBDBM22760(2-hydroxy-1,2-bis(4-methoxyphenyl)ethan-1-one | Be...)
Affinity DataKi: >1.00E+5nMAssay Description:CE inhibition was determined using a spectrophotometric multiwell plate assay with o-NPA as a substrate. The rate of change in absorbance at 420 nm w...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/15/2008
Entry Details Article
PubMed
TargetLiver carboxylesterase 1(Human)
University of Mississippi

LigandPNGBDBM22760(2-hydroxy-1,2-bis(4-methoxyphenyl)ethan-1-one | Be...)
Affinity DataKi: >1.00E+5nMAssay Description:CE inhibition was determined using a spectrophotometric multiwell plate assay with o-NPA as a substrate. The rate of change in absorbance at 420 nm w...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/15/2008
Entry Details Article
PubMed
TargetAcetylcholinesterase(Human)
University of Mississippi

LigandPNGBDBM22760(2-hydroxy-1,2-bis(4-methoxyphenyl)ethan-1-one | Be...)
Affinity DataKi: >1.00E+5nMAssay Description:CE inhibition was determined using a spectrophotometric multiwell plate assay with o-NPA as a substrate. The rate of change in absorbance at 420 nm w...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/15/2008
Entry Details Article
PubMed
TargetCholinesterase(Human)
University of Mississippi

LigandPNGBDBM22760(2-hydroxy-1,2-bis(4-methoxyphenyl)ethan-1-one | Be...)
Affinity DataKi: >1.00E+5nMAssay Description:CE inhibition was determined using a spectrophotometric multiwell plate assay with o-NPA as a substrate. The rate of change in absorbance at 420 nm w...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/15/2008
Entry Details Article
PubMed